Separating Fact From Fiction: Can Creatine Cause Headaches?

in News

​​The Dark Side: Can Creatine Cause Headaches?

Creatine is a famous supplement that has been used by bodybuilders for decades to boost performance and building muscle mass. It's also been linked to improved mental focus and better overall health. But despite its many benefits, there are some potential side effects associated with creatine use — including headaches. Here, we'll explore the potential link between creatine and headaches, as well as how you can reduce your risk of experiencing them. We'll also discuss other possible causes of headache pain so you can get the relief you need more quickly. So if you think creatine administration could be causing your headaches, read on to learn more about what may be going on in your body!

Side Effects: Can Creatine Cause Headaches?

However, like any supplement, creatine can have potential side effects. Headaches are among the most common of these side effects, and they can range from mild to severe. Unfortunately, the exact cause of headaches related to creatine use is unclear. Some believe that it could be a result of dehydration or low electrolyte levels due to increased water loss from exercise. Others speculate that it could be an allergic reaction or sensitivity to the supplement itself.

The good news is there are methods to reduce your risk of experiencing headaches due to creatine supplements use. For starters, make sure you're drinking plenty of water throughout the day and filling electrolytes lost through sweat. Additionally, some people find that taking creatine with a meal helps reduce the risk of headaches. If you do experience any discomfort, it's recommended to cut back on your dosage or stop using the supplement altogether until symptoms improve.

Headache is a commonly reported side effect of creatine use. In a study involving 72 healthy adults, two participants reported mild headaches as a side effect. Another study revealed that 1 out of 20 participants experienced headaches after taking the supplement. The cause of the headache is not clear, but some believe it could be due to dehydration or an allergic reaction to the supplement.

What Are The Possible Reasons Why Creatine Could Cause Headaches?

There are several possible reasons why creatine supplementation may cause headaches in some individuals. Some of these reasons include the following:


Creatine as a naturally occurring substance has been shown to increase water retention in the body and muscle tissues, which can lead to dehydration if adequate water intake is not maintained. This is because creatine binds with water molecules, and as it moves through the cells, it draws more water in with it. When too much of the body's water is bound up in this way, dehydration can occur, resulting in headaches.

Low Electrolytes

The creatine supplement can also cause an imbalance in electrolyte levels due to increased water loss from exercise. Electrolytes are minerals that help the body properly absorb and transport nutrients and fluids throughout the body. Low electrolyte levels can lead to dehydration, which is often accompanied by a headache.

Alterations In Blood Flow

Creatine supplementation has been linked to increased blood flow to the muscles, which could result in alterations in blood flow to other areas of the body, including the brain. Studies have shown that creatine can lead to an increase in cerebral blood flow, which can result in increased oxygen delivery and metabolic activity in the brain. This altered blood flow can cause headaches in some people.

Increased Stress On The Liver And Kidneys

Creatine supplementation has been linked to increased stress on the liver and kidneys as these organs work to process and excrete the compound. This can direct to an increase in metabolic activity and energy production, which can result in an overload of toxins in the body. This overload of toxins can affect the brain, causing headaches in some people. Additionally, increased metabolic activity can lead to fatigue, which can also have part in the development of headaches.

Individual Sensitivity

It is possible that individuals may be more sensitive to creatine than others, leading to the development of headaches. This could be due to an underlying medical condition or an allergic reaction to the supplement itself. Some individuals may also have a genetic predisposition that makes them more prone to adverse reactions from creatine. Research has shown that certain genetic markers can increase the risk of experiencing side effects from creatine supplementation. It is important to note that these genetic markers can vary from person to person, so it is best to consult a doctor if you are concerned about possible reactions.

Factors That May Increase The Likelihood Of Headaches With Creatine

Several factors can increase the likelihood of experiencing headaches while taking creatine. These include:


Taking high doses of creatine can increase the risk of developing headaches. According to the International Society of Sports Nutrition, the recommended dosage for creatine supplementation is 0.1 g/kg/day, or about 5-10 grams per day, taken in divided doses. If a higher dosage is taken, it may increase the risk of headaches.

Hydration Status

As mentioned earlier, dehydration can be a contributing factor to headaches in some individuals. Creatine supplementation has been shown to increase water retention in the body, and it's important to maintain adequate hydration levels while taking creatine to minimize the risk of dehydration and associated headaches.

Timing Of Supplementation

Studies have suggested that supplementing with creatine after exercise can increase the risk of headaches. It is recommended to take the supplement in divided doses throughout the day, not just after exercise. This can help reduce the likelihood of developing a headache due to dehydration or other side effects.

Pre-Existing Medical Conditions

Certain medical conditions, such as heart disease and high blood pressure, may increase the risk of developing headaches while taking creatine. High blood pressure can restrict the flow of oxygen and nutrients to the brain, which can lead to tension headaches and other forms of headache pain. Additionally, those who suffer from kidney disease or any form of the renal disorder may be more likely to experience headaches when taking creatine. It is important to discuss any pre-existing conditions with your doctor before beginning a creatine supplementation regimen.

Interaction With Other Medications Or Supplements

Creatine can interact with some medications and supplements, which may increase the risk of developing headaches. For example, individuals taking diuretics or ACE inhibitors are at a higher risk of experiencing headaches when taking creatine. Additionally, those who take other supplements such as caffeine, guarana, ephedra, and ginseng may be more likely to experience headaches due to the combined effect of these substances.

Minimizing The Risk: How To Avoid Headaches From Creatine?

If you are concerned about developing headaches while taking creatine, there are several steps you can take to minimize the risk:

Start With A Low Dose

Starting with a low or optimal dose of creatine, such as 3 grams per day, can help minimize the risk of developing headaches. If you tolerate this dose well, you can gradually increase the dose to the recommended levels.

Stay Hydrated

Stay hydrated while taking creatine in order to reduce the risk of headaches. Aim to drink at least 8 to 10 glasses of water a day, and consider adding electrolytes to your water to help maintain proper hydration levels. Electrolytes are minerals that can help balance fluids in the body and support optimal hydration.

Take With Food

Taking creatine with a meal or snack can help reduce the risk of developing headaches. This is due to the fact that food consumption helps to maintain blood sugar levels, which prevents dehydration and other side effects such as headaches. Additionally, taking creatine with food may also improve the absorption of the supplement in some cases.

Monitor Your Symptoms

If you experience headaches while taking creatine, it's important to monitor your symptoms and prevent creatine headaches. It is important to keep track of other factors that can contribute to headache pain and muscle cramps, such as dehydration status, the timing of supplementation, and pre-existing medical conditions. If any of these conditions are present, it may be necessary to adjust your supplementation regimen or consult a doctor for further advice.

Avoid High Doses

High doses of creatine supplements, such as 20 grams per day or more, can increase the risk of developing headaches. It is important to stay within the recommended dosage range and discuss any questions with your healthcare provider before taking higher doses. Additionally, it may be beneficial to spread out your supplementation throughout the day rather than taking all of it at once.

Consider Cycling

Cycling on and off starting creatine supplementation may help reduce the risk of developing headaches. For example, you could take creatine for 8-12 weeks, then take a break for 4-6 weeks before starting again. Cycling may also help prevent any potential long-term side effects that can develop from taking creatine for an extended period of time. 

Try Create's Products!

If you are looking for a quality, science-backed supplement to help meet your fitness and performance goals, try Create's products. Our team of experts has formulated our supplements with the highest quality ingredients to ensure optimal results. The creatine monohydrate gummies are particularly popular for those who want a convenient and delicious way to get their daily dose of creatine.